1. When David is being interrogated by the FBI immediately after Dr. Kleinman's death, he thinks, "Why should he be responsible for keeping the secret? He hadn't asked for this." Why does David choose not to reveal what he knows to the FBI?
2. Monique and David haven't seen each other in nearly twenty years when he arrives on her doorstep in Princeton. Why does David seek out Monique for help? Why does Monique, in turn, risk her life to aid David? Is it merely academic interest that compels her to accompany him on his dangerous quest, or is there something more?
3. Karen refuses to believe the FBI when they tell her that David is wanted for murder and selling drugs. Given her contentious personal history with David, why does she stand by her ex-husband? What makes her so certain that he's not involved in these illegal activities?
4. Discuss the novel's narrative structure and plotting. Did you guess the identity of Henry Cobb before it was revealed? What did you find to be most compelling about Final Theory
-- the action scenes, the characters, the scientific and historical information, or something else entirely?
5. Why do you suppose the author chose to give Simon, a cold-blooded killer-for-hire, such a sympathetic back story? Was he a convincing villain? Did you empathize with him at all, given that he lost his wife and children because of an American military error in Chechnya? Why or why not?