3.2 Mirko Beljanski and RNA Fragments
We have seen that in the cell, DNA is like a library containing all genetic information. But what activates DNA, and what makes it enter into mitosis (the multiplication of the cell)? And, on the other hand, what are the factors that put the DNA to rest or block it, and thereby prevent it from working normally?
Biologist Mirko Beljanski (1923-1998) specifically studied DNA activity.1 Many chemical factors, like hormones, can activate cell DNA through binding at specific sites. Conversely, poisons and heavy metals, as well as gamma and X-rays, are capable of damaging, even destroying DNA, either directly through a toxic action or through free radical intermediaries.
A little under forty years ago Mirko Beljanski showed for the first time in history that DNA replication and hence cell proliferation could be both blocked and accelerated using RNA fragments.2 Through his experiments he showed that the DNA’s actions were, among other factors, contingent upon small RNA molecules. Thus, tiny segments of RNA (primer RNA) can prime the division of normal cells,3 while other RNA are capable of stimulating the division of cancerous cells at different sites. There also exist certain types of RNA (antisense RNA) of specific lengths that hinder the division of cancerous cells or viral DNA.
The results of Mirko Beljanski’s experiments on antisense, antiviral, and anti-cancer RNA were reconfirmed in the 1980s by several American research teams.4 The 2004 announcement in France by CNRS--Généthon d’Evry Laboratory of a possible victory over the serious genetic disorder of myopathy thanks to RNA-fragments was the logical follow-up to his pioneering work.5
In effect, biologists that practice gene therapy no longer seek to fully replace a defective gene, but rather to mask pathological DNA with antisense RNA fragments--without interfering with transcription of the remaining healthy genetic information. This little RNA is carried by a virus that enters the cell. The artificial infection it induces allows the antisense RNA encoded to the virus to be expressed.
The use of antisense RNA fragments to modulate--here, to mask--the activity of a defective, very precisely targeted DNA is once again generating interest in the study of the human genome for treatment of genetic disorders and perhaps also for the treatment of other types of degenerative diseases. Normal DNA stimulated by a primer Cancerous DNA stimulated by another RNA primer of different length and sequence and at a different site Cancerous DNA or pro-viral DNA blocked by antisense RNA RNA primer RNA primer RNA antigens The first stimulates healthy tissue DNA The second stimulates cancerous tissue DNA The third blocks pro-viral cancerous DNA.
Even if today’s researchers for the most part ignore the long and meticulous RNA research he conducted more than 30 years ago, Mirko Beljanski can be considered to be the visionary forerunner of the most advanced biological technologies used today in genetic engineering . ..
Beginning in 1975, in search of a means to reinforce the failing immune system of cancer patients undergoing chemo- or radiation therapy, Mirko Beljanski identified tiny RNA primers specific to bone marrow stem cells. He injected them into a severely immuno-deficient rabbit and found that these RNA were able, within 48 hours, to restore the rabbit’s leukocyte population and platelet counts.
Likewise, for 25 years these tiny RNA primers have saved lives in humans by reestablishing the number of leukocytes, lymphocytes, and platelets in the blood by stimulating the DNA of bone marrow stem cells. Unfortunately, because they only weakly prime red blood cell precursors, they are not useful for treating anemia.
After the RNA have served as primers, they are broken down into nucleic acid building blocks that can repair DNA damaged by radiation or by chemotherapy products during treatment of cancer patients. Mirko Beljanski has also demonstrated this protective role for DNA structure.
Groups of mice that underwent radiation at 90 percent of the lethal dose for their species and size were also significantly protected by taking these RNA fragments. Moreover, during the five subsequent generations after this deadly radiation treatment, the young mice showed no phenotypical deficiencies visible on their bodies, reflecting the integrity of their parents’ germinal cells and of the protection provided by the RNA fragments.
The immune stimulant/regulatory potential of RNA fragments is an invaluable advancement for anti-aging medicine. Linking nutrition with RNA-fragments is a simple way to reinvigorate a weakened immunity.
The protective power of these same RNA against radiation could be an added benefit to modern humans, who are now exposed to increasingly worrisome levels of electromagnetic pollution. In addition to the increased intensity of natural UVB rays due to the enlargement of the ozone hole at Earth’s poles, we are exposed to medical exam X-rays, GSM cell phone emissions of electromagnetic energy, and relay antennas and wireless terminals. These antennas, located practically everywhere in our towns, are beginning to create a new danger, that of ELF (extremely low frequency), the long-term consequences of which (such as carcinogenic effects on living beings) no one can yet predict.
Therefore, taking these reparatory RNA fragments regularly is a good way to guard against new environmental aggressions. It is recommended that they be taken in consistent treatments over the course of the year for all regular computer and cell phone users, as well as for all those who are passively subjected to relay antenna and wireless terminal radiations, which is to say practically everyone!